A new two-layer passive micromixer design based on SAR-vortex principles

Abstract

Abstract Micromixers are key components of microfluidic systems for sample analysis, bioreactors, drug delivery, and many other applications. To date, numerous passive micromixer designs have been proposed. Among those, several designs with complex design structures have been demonstrated to be efficient. In the present work, the authors try to propose a new efficient design with low complexity in terms of fabrication. The new design is two-layer and is based on the split and recombination (SAR) and vortex mixing principles. It is suggested to fabricate the new design in polydimethylsiloxane (PDMS) using the soft lithography technique. This new design is chosen among three new designs simulated using the computational fluid dynamics (CFD) software ANSYS Fluent 17.0. The three new designs are named ND1, ND2, and ND3 and their mixing performances are evaluated numerically using mixing index (MI) and mixer effectiveness (ME) quantities at four different Reynolds (Re) numbers in the range of 0.1–100. Calculated values are compared with those obtained for the classical Y-shaped (CY) micromixer. Flow and mixing patterns are computed by solving the continuity, Navier–Stokes, and the convection–diffusion equations. CFD results for the CY micromixer are compared with available experimental and numerical data and reasonable agreement is observed. According to the results, ND3 has the highest performance (ME up to 36.86 percent/mm) among the investigated micromixer designs in the entire range of Re numbers. The maximum pressure drop (35099.9 Pa at Re = 100 for ND3) is still in the range of acceptable pressure drops reported in the literature. ND3 can be used as an efficient substitute for CY. Although ND3 is highly efficient (MI up to 99.52%) at Re numbers lower than 0.3 or higher than 50, its performance at the intermediate Re numbers (0.3 < Re < 50) is poor and unacceptable (MI as low as 44%). This can be simply improved by adding extra mixing units to provide adequate mixing also at the intermediate Re numbers.