Pain pharmacogenetics-Reference-Cited by-同舟云学术

Pain pharmacogenetics

Published:2020-08-04 Issue:0 Volume:0 Page:
ISSN:2363-8915
Container-title:Drug Metabolism and Personalized Therapy
language:
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Author:

Slepukhina Mariia A.¹,Ivashchenko Dmitriy V.²,Sheina Maria A.³,Muradian Andranik Alexandrovich⁴,Blagovestnov Dmitriy Alexeevich⁴,Sychev Dmitriy A.⁵

Affiliation:

1. I.M. Sechenov First Moscow State Medical University, Moscow 119146, Russia

2. Child Psychiatry and Psychotherapy Department, Department of Personalized Medicine, Russian Medical Academy of Continuous Professional Education, Moscow, Russia

3. Department of Anesthesiology and Intensive Care, I.M. Sechenov First Moscow State Medical University, Moscow 119146, Russia

4. Department of Urgent and General Surgery, Russian Medical Academy of Continuous Professional Education, 2/1, Barrikadnaya St., Moscow 125993, Russia

5. Department of Clinical Pharmacology and Therapeutics, Russian Medical Academy of Continuous Professional Education, Moscow, Russia

Abstract

AbstractPain is a significant problem in medicine. The use of PGx markers to personalize postoperative analgesia can increase its effectiveness and avoid undesirable reactions. This article describes the mechanisms of nociception and antinociception and shows the pathophysiological mechanisms of pain in the human body. The main subject of this article is pharmacogenetic approach to the selection of anesthetics. Current review presents data for local and general anesthetics, opioids, and non-steroidal anti-inflammatory drugs. None of the anesthetics currently has clinical guidelines for pharmacogenetic testing. This literature review summarizes the results of original research available, to date, and draws attention to this area.

Publisher

Walter de Gruyter GmbH

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics

Link

https://www.degruyter.com/document/doi/10.1515/dmpt-2020-2939/pdf

Reference244 articles.

1. CYP2B6*6allele and age substantially reduce steady-state ketamine clearance in chronic pain patients: impact on adverse effects;Br J Clin Pharmacol,2015

2. CYP2D6 pharmacogenetic and oxycodone pharmacokinetic association study in pediatric surgical patients;Pharmacogenomics,2017

3. A neurological basis for the observed peripheral sensory modulation of emotional responses;Traumatology,2005

4. “Brave Men” and “Emotional Women: a theory-guided literature review on gender bias in health care and gendered norms towards patients with chronic pain;Pain Res Manag,2018

5. Endocannabinoid system and pain: an introduction;Proc Nutr Soc,2014

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