Notizen: Einfache, schonende Synthese von Aminosäuremethyl- und benzylestern.

Author:

Weber U.1

Affiliation:

1. Physiologisch-chemisches Institut, Universität Tübingen

Abstract

Methyl- and benzylesters of acid labile amino acids are obtained as their hydrochlorides or BF3-complexes by reaction of the N-protected amino acid with benzylalcohol (methanol), DCC, HOBt and pyridine and subsequent cleavage of the N-protection group by HCl in acetic acid or bortrifluorideetherate in acetic acid.

Publisher

Walter de Gruyter GmbH

Subject

General Chemistry

Cited by 11 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Hydrogenolytic debenzylation of sulfur-containing peptides;International Journal of Peptide and Protein Research;2009-01-12

2. Activation of carboxylic acids by pyrocarbonates;International Journal of Peptide and Protein Research;2009-01-12

3. Second supplementary list of amino-acid derivatives useful in peptide synthesis;International Journal of Peptide and Protein Research;2009-01-12

4. Preparation of Esters;Compendium of Organic Synthetic Methods;2006-11-22

5. Der 2,4,6-Triisopropylbenzolsulfonyl(Tip)-Rest, eine neue Schutzgruppe für die Guanidinofunktion von Arginin / The 2,4,6-Triisopropylbenzenesulfonyl Residue, a New Protecting Group for the Guanidino Function of Arginine;Zeitschrift für Naturforschung B;1987-12-01

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