Chitosan nanocomposite film incorporating <i>Nigella sativa</i> oil, <i>Azadirachta indica</i> leaves’ extract, and silver nanoparticles-Reference-Cited by-同舟云学术

Chitosan nanocomposite film incorporating Nigella sativa oil, Azadirachta indica leaves’ extract, and silver nanoparticles

Published:2023-01-01 Issue:1 Volume:23 Page:
ISSN:1618-7229
Container-title:e-Polymers
language:en
Short-container-title:

Author:

Batubara Afnan S.¹,Obaid Najla A.²,Alharbi Hanan M.²,Altalhi Turki Mohammed¹,Alasmari Mohammed Abdullah¹,Alghamdi Ammar Zuhair¹,Sharmin Eram¹

Affiliation:

1. Department of Pharmaceutical Chemistry , College of Pharmacy , Umm Al-Qura University , Makkah , 21955 , Saudi Arabia

2. Department of Pharmaceutics , College of Pharmacy , Umm Al-Qura University , Makkah , 21955 , Saudi Arabia

Abstract

Abstract Nanocomposite films have been prepared from chitosan, cinnamaldehyde, Nigella sativa or blackseed oil, and silver nanoparticles (NPs) biosynthesized in Azadirachta indica or neem leaves’ extract. The methodology involved simple blending of components through “green chemistry” route. The films obtained were soft and foldable. The morphology by scanning electron microscopy confirmed the inclusion of NPs in the films. Microbial penetration study demonstrated that the films offered good resistance to secondary bacterial infection. The antibacterial study against Staphylococcus aureus (ATCC 29213) and E. coli (ATCC 25922) indicated moderate antibacterial behavior of the films. The swelling behavior in water, phosphate buffer saline, and simulated wound fluid was found to be appropriate for use as wound dressings. The films were biodegradable in soil and showed good thermal stability up to 200°C.

Publisher

Walter de Gruyter GmbH

Subject

Polymers and Plastics,Physical and Theoretical Chemistry,General Chemical Engineering

Link

https://www.degruyter.com/document/doi/10.1515/epoly-2022-8083/pdf

Reference23 articles.

1. Toczek JA, Sadłocha MA, Major K, Stojko RA. Benefit of silver and gold nanoparticles in wound healing process after endometrial cancer protocol. Biomedicines. 2022;10(3):679–89. 10.3390/biomedicines10030679.

2. Jugreet BS, Suroowan S, Rengasamy RRK, Mahomoodally MF. Chemistry, bioactivities, mode of action and industrial applications of essential oils. Trends Food Sci Technol. 2020;101:89–105. 10.1016/j.tifs.2020.04.025.

3. Kashyap M, Archana D, Semwal A, Dutta J, Dutta PK. Chitosan: A promising substrate for regenerative medicine in drug formulation. In: Dutta KP, editor. Chitin and Chitosan for Regenerative Medicine. New Delhi: Springer India; 2016. p. 261–77.

4. Wardana AA, Kingwascharapong P, Tanaka F, Tanaka F. CuO nanoparticles/Indonesian cedarwood essential oil-loaded chitosan coating film: characterisation and antifungal improvement against Penicillium spp. Int J Food Sci Technol. 2021;56(9):4224–38. 10.1111/ijfs.15195.

5. Ali A, Shahid MA, Hossain MD, Islam MN. Antibacterial bi-layered polyvinyl alcohol (PVA)-chitosan blend nanofibrous mat loaded with Azadirachta indica (neem) extract. Int J Biol Macromol. 2019;138:13–20. 10.1016/j.ijbiomac.2019.07.015.

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Development and characterization of chitosan film containing hydroethanolic extract of Coffea arabica leaves for wound dressing application;Materials Today Communications;2024-03

2. A blue fluorescent waterborne polyurethane-based Zn(ii) complex with antibacterial activity;e-Polymers;2024-01-01

3. Preparation of cardanol-based curing agent for underwater drainage pipeline repairs;e-Polymers;2024-01-01