Affiliation:
1. School of Science, Mae Fah Luang University, Ta-sud, Muang , Chiang Rai 57100 , Thailand
Abstract
Abstract
Plant antioxidants can be applied in the management of various human diseases. Despite these, extraction of these compounds still suffers from residual solvent impurities, low recovery yields, and the risks of undesirable chemical changes. Inspired by the protein–lipid interactions in the cell membranes, we proposed using poly(styrene-alt-maleic acid) (PSMA) to destabilize and associate with the bilayer lipids into the membrane-like nanodiscs. Such nanostructures could serve as protective reservoirs for the active compounds to reside with preserved bioactivities. This concept was demonstrated in the antioxidant extraction from robusta coffee leaves. Results indicated that aqueous PSMA extraction (no buffer agent) yielded products with the highest contents of phenolic acids (11.6 mg GAE·g−1) and flavonoids (9.6 mg CE·g−1). They also showed the highest antioxidant activity (IC50 = 3.7 µg·mL−1) compared to those obtained by typical sodium dodecyl sulfate and water extraction. This biomimetic approach could be considered for developing environmentally friendly extraction protocols in the future.
Subject
Polymers and Plastics,Physical and Theoretical Chemistry,General Chemical Engineering
Reference39 articles.
1. Kasote DM, Katyare SS, Hegde MV, Bae H. Significance of antioxidant potential of plants and its relevance to therapeutic applications. Int J Biol Sci. 2015;11(8):982–91. 10.7150/ijbs.12096.
2. Adebooye OC, Alashi AM, Aluko RE. A brief review on emerging trends in global polyphenol research. J Food Biochem. 2018;42(4):e12519. 10.1111/jfbc.12519.
3. Sy Mohamad SF, Mohd Said F, Abdul Munaim MS, Mohamad S, Azizi Wan Sulaiman WM. Application of experimental designs and response surface methods in screening and optimization of reverse micellar extraction. Crit Rev Biotechnol. 2020;40(3):341–56. 10.1080/07388551.2020.1712321.
4. Miłek M, Legáth J. Extraction of flavonoids from medicinal plants with use of various solvents systems. Proceedings of the Scientific Researches in Food Production-3rd Meeting of Young Researchers from V4 Countries. Debrecen, Hungary: 2018 Dec 7.
5. Chemat F, Abert Vian M, Ravi HK, Khadhraoui B, Hilali S, Perino S, et al. Review of alternative solvents for green extraction of food and natural products: Panorama, principles, applications and prospects. Molecules. 2019;24(16):3007.
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献