Current updates on various treatment approaches in the early management of acute spinal cord injury

Author:

Fiani Brian1,Arshad Mohammad Arsal1,Shaikh Emad Salman2,Baig Aqsa3,Farooqui Mudassir4,Ayub Muhammed Abubakar5,Zafar Atif4,Quadri Syed A.5

Affiliation:

1. Department of Neurosurgery , Desert Regional Medical Center , 1150 N. Indian Canyon Drive , Palm Springs , CA 92262 , USA

2. Department of Physical Medicine & Rehabilitation , Spaulding Rehabilitation Hospital, Harvard Medical School , Boston , MA , USA

3. Liaquat National Hospital and Medical College , Karachi , Pakistan

4. Department of Neurology , University of New Mexico , Albuquerque , NM , USA

5. Department of Neurology , Massachusetts General Hospital, Harvard Medical School , Boston , MA , USA

Abstract

Abstract Spinal cord injury (SCI) is a debilitating condition which often leads to a severe disability and ultimately impact patient’s physical, psychological, and social well-being. The management of acute SCI has evolved over the couple of decades due to improved understanding of injury mechanisms and increasing knowledge of disease. Currently, the early management of acute SCI patient includes pharmacological agents, surgical intervention and newly experimental neuroprotective strategies. However, many controversial areas are still surrounding in the current treatment strategies for acute SCI, including the optimal timing of surgical intervention, early versus delayed decompression outcome benefits, the use of methylprednisolone. Due to the lack of consensus, the optimal standard of care has been varied across treatment centres. The authors have shed a light on the current updates on early treatment approaches and neuroprotective strategies in the initial management of acute SCI in order to protect the early neurologic injury and reduce the future disability.

Publisher

Walter de Gruyter GmbH

Subject

General Neuroscience

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