Phytochemical, Morphological, and Biological Investigations of Propolis from Central Chile

Author:

Valcic Susanne1,Montenegro Gloria2,Mujica Ana-Maria2,Avila Guacolda2,Franzblau Scott3,Singh Maya P.4,Maiese William M.4,Timmermann Barbara N.1

Affiliation:

1. Department of Pharmacology and Toxicology, College of Pharmacy, The University of Arizona, Tucson, AZ 85721, U.S.A.

2. Departamento de Ecología, Pontificia Universidad Católica de Chile, Casilla 114-D. Santiago, Chile

3. Pharmacology Research Department, Laboratory Research Branch, Gillis W. Long Hansen’s Disease Center, Baton Rouge, LA 70894, U.S.A.

4. Natural Products Research Section, Wyeth-Ayerst Research, 401 N. Middletown Road, Pearl River, New York 10965, U.S.A.

Abstract

Abstract Propolis from Central Chile was investigated for its plant origin by microscopical analysis of pollen grains and leaf fragments found in the sample. The pollen grains that appear with significant higher frequency in the sample corresponded to four native and two introduced species, whereas leaf fragments corresponded to four native species. Seventeen phenolic com­ pounds that belong to the phenylpropane, benzaldehyde, dihydrobenzofuran, or benzopyran classes, were isolated from an organic extract that was found to have a moderate growth inhibitory activity against Mycobacterium avium , M. tuberculosis, and two strains of Staphylococcus aureus. The components responsible for activity were determined.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

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