n-Alkylresorcinol Occurrence in Mercurialis perennis L. (Euphorbiaceae)

Author:

Lorenz Peter1,Knödler Matthias1,Bertrams Julia1,Berger Melanie1,Meyer Ulrich1,Stintzing Florian C.1

Affiliation:

1. WALA Heilmittel GmbH, Department of Research & Development, Dorfstraße 1, D-73087 Bad Boll/Eckwälden, Germany

Abstract

Investigation of the dichloromethane extracts from herbal and root parts of Mercurialis perennis L. afforded a mixture of 11 homologous n-alkylresorcinols (ARs) with saturated odd-numbered alkyl side chains (C15:0-C27:0). In addition to three predominant ARs (C19:0, C21:0 and C23:0), a number of minor ARs were identified by use of LC-MS/MS and GC-MS techniques. Among the compounds detected, four uncommon ARs with evennumbered alkyl side chain lengths were also determined. The overall AR concentration in herbal parts was 7 to 9 times higher compared to that of the roots. The results presented may open a new view on the phytochemistry and pharmacognosy of M. perennis and other members of the Euphorbiaceae family.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

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