Affiliation:
1. Department of Pharmacognosy, University of Vienna, PharmaCenter, Althanstraße 14, A-1090 Vienna, Austria
2. Institute of Pharmacognosy and Botany, Comenius University, Pharmaceutical Faculty, Odbojarov 10, SK-83232 Bratislava, Slovakia
3. Institute of Pharmaceutical Sciences, Karl-Franzens-Universit¨at Graz, Universit¨atsplatz 1, A-8010 Graz, Austria
Abstract
The investigation of a dichloromethane extract of flower heads of Achillea clypeolata collected in Bulgaria led to the isolation of one guaiane (4,10,11-trihydroxy-guaiane, 1), four eudesmanes (4(15)-eudesmene-1β ,11-diol, 2, clypeotriol, 3, 3-epi-clypeotriol, 4, cryptomeridiol, 5), one diterpene (sugeroside, 6) and two phenolic compounds (centaureidin, 7 and scopoletin, 8). Their structures were elucidated by UV/vis, EI- and CI-MS as well as by one- and two-dimensional NMR experiments. 4,10,11-Trihydroxy-guaiane (1) and 3-epi-clypeotriol (4) are reported here for the first time.
Cited by
17 articles.
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