1. Pharmaceutical Biochemistry and Bioanalytics, Pharmaceutical Institute , University of Bonn , An der Immenburg 4, D-53121 Bonn , Germany
2. Institutes I & II of Pharmacology, Center of Pharmacology, Faculty of Medicine and University Hospital Cologne , University of Cologne , D-50931 Cologne , Germany
3. Faculty of Applied Natural Sciences , TH Köln-University of Applied Sciences , Campus Leverkusen, D-51379 Leverkusen , Germany