A Major Saponin from Leaves Extract of Acer velutinum-Reference-Cited by-同舟云学术

A Major Saponin from Leaves Extract of Acer velutinum

Published:2009-09-01 Issue:9 Volume:64 Page:1081-1086
ISSN:1865-7117
Container-title:Zeitschrift für Naturforschung B
language:en
Short-container-title:

Author:

Glénsk Michał¹,Włodarczyk Maciej¹,Bassarello Carla²,Pizza Cosimo²,Stefanowicz Piotr³,Świtalska Marta⁴

Affiliation:

1. Department of Pharmacognosy, WroclawMedical University, Nankiera 1, 50-140 Wrocław, Poland

2. Universito Ricercatore di Biologia Farmaceutica Dipartimento di Scienze Farmaceutiche Università degli studi di Salerno, via Ponte don Melillo, 84084 Fisciano, Italy

3. Faculty of Chemistry, Wroclaw University, F. Joliot-Curie 14, 50-383 Wrocław, Poland

4. Department of Experimental Oncology, Institute of Immunology and Experimental Therapy, 12 R. Weigla St., 53-114 Wroclaw, Poland

Abstract

A major triterpenoid saponin was isolated from the leaves extract of Acer velutinum. This compound was characterized as 21β ,22α-O-diangeloylprotoaescigenin 3-O-[β -D-glucopyranosyl- (1→2)][β -D-glucopyranosyl-(1→4)]-β -D-glucuronopyranosyl acid. Its structure was elucidated by 1H, gCOSY, ROESY, gHSQC, gHMBC NMR as well as ESI-MS experiments. Isolated saponin exhibited in vitro cytotoxicity against HL-60, B16-F0 and BALB/3T3 cell lines.

Publisher

Walter de Gruyter GmbH

Subject

General Chemistry

Link

https://www.degruyter.com/document/doi/10.1515/znb-2009-0915/pdf

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