3-Substituted Coumarins from the Twigs of Rhadinothamnus rudis ssp. amblycarpus

Author:

Girard Corinne1,Roux Delphine2,Muyard Frédéric2,Colombain Michel2,Tillequin François3,Waterman Peter G.4,Bévalota Françoise2

Affiliation:

1. 1Laboratoire de Pharmacognosie, EA3921 Optimisation Métabolique et Cellulaire, UFR des Sciences M´edicales et Pharmaceutiques, Place Saint-Jacques, 25030 Besançon Cedex, France

2. 2Laboratoire de Pharmacognosie, EA3921 Optimisation Métabolique et Cellulaire, UFR des Sciences Médicales et Pharmaceutiques, Place Saint-Jacques, 25030 Besançon Cedex, France

3. 3Laboratoire de Pharmacognosie de l’Université René Descartes, U.M.R./C.N.R.S.N° 8638, Faculté des Sciences Pharmaceutiques et Biologiques, 4 Avenue de l’Observatoire, 75006 Paris, France

4. 4Centre for Phytochemistry and Pharmacology, Southern Cross University, PO Box 157, Lismore, NSW 2480, Australia

Abstract

The twigs of Rhadinothamnus rudis ssp. amblycarpus (Phebalium rude ssp. amblycarpum) yielded three new 3-substituted coumarins: rudicoumarin A-C (1- 3). Their structures were established on the basis of their NMR and mass spectral data. In addition, ten other known compounds were also isolated, including phebaclavin I, schinicoumarin, seselin, and seven linear furocoumarins.

Publisher

Walter de Gruyter GmbH

Subject

General Chemistry

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