Author:
Stelzl Evelyn,Appel Hannah M.,Mehta Rochak,Marins Ed G.,Berg Jörg,Paar Christian,Zurl Hanna,Santner Brigitte I.,Kessler Harald H.
Abstract
Abstract
Background:
Determination of the hepatitis C virus (HCV) genotype and discrimination between HCV subtypes 1a and 1b is still mandatory prior to anti-HCV treatment initiation. The aim of this study was to evaluate the performance of the recently introduced cobas
Methods:
The cobas
Results:
When accuracy was tested, panel members containing HCV subtypes 1a, 1b, and 3a were identified as expected; however, the new assay failed to identify low titer panel members containing HCV subtype 5a correctly. Of 183 clinical samples, 160 gave concordant results. For seven samples, an indeterminate result was reported with the cobas
Conclusions:
The cobas
Subject
Biochemistry (medical),Clinical Biochemistry,General Medicine
Cited by
14 articles.
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