Synthesis and Antimicrobial Evaluation of Some New 2-(6-Oxo-5,6- dihydro[1,3]thiazolo[3,2-b]-2-aryloxymethyl-1,2,4-triazol-5-yl)-Narylacetamides

Author:

Lobo Prajwal L.1,Poojary Boja1,Manjunatha Kumsi1,Kumari Nalilu Suchetha2

Affiliation:

1. Department of Chemistry, Mangalore University, Mangalagangothri-574199, Karnataka, India

2. Department of Biochemistry, K. S. Hegde Medical Academy, Deralakatte-574162, Karnataka, India

Abstract

A series of 2-(6-oxo-5,6-dihydro[1,3]thiazolo[3,2-b]-2-aryloxymethyl-1,2,4-triazol-5-yl)-Narylacetamides 6 were synthesized in good yield by condensing 5-aryloxymethyl-4H-1,2,4-triazole- 3-thiol 5 with various substituted N-phenyl-maleimides in acetic acid media. The newly synthesized compounds were characterized by spectral data and tested for their in vitro antibacterial and antifungal activity against a variety of microorganisms.

Publisher

Walter de Gruyter GmbH

Subject

General Chemistry

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