The antibacterial and cytocompatibility of the polyurethane nanofibrous scaffold containing curcumin for wound healing applications-Reference-Cited by-同舟云学术

The antibacterial and cytocompatibility of the polyurethane nanofibrous scaffold containing curcumin for wound healing applications

Published:2023-04-05 Issue:6 Volume:114 Page:505-513
ISSN:1862-5282
Container-title:International Journal of Materials Research
language:en
Short-container-title:

Author:

Abdelbasset Walid Kamal¹²^ORCID,Jasim Saade Abdalkareem³,Abed Azher M.⁴,Altimari Usama S.⁵,Eid Marwa M.⁶,Karim Yasir Salam⁷,Elkholi Safaa M.⁸,Mustafa Yasser Fakri⁹,Jalil Abduladheem Turki¹⁰¹¹

Affiliation:

1. Department of Health and Rehabilitation Sciences , College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University , P.O. Box. 173 , Al-Kharj 11942 , Saudi Arabia

2. Department of Physical Therapy , Kasr Al-Aini Hospital, Cairo University , Giza 12613 , Egypt

3. Medical Laboratory Techniques Department , Al-maarif University College , Al-Anbar-Ramadi , Iraq

4. Department of Air conditioning and Refrigeration , Al-Mustaqbal University College , Babylon , Iraq

5. Al-Nisour University College , Baghdad , Iraq

6. Department of Physical Therapy , College of Applied Medical Sciences, Taif University, Taif University , P.O. Box. 11099 , Taif 21944 , Saudi Arabia

7. Al-Manara College For Medical Sciences , Maysan , Iraq

8. Department of Rehabilitation Sciences , College of Health and Rehabilitation Sciences, Princess Nourah bint Abdulrahman University , P.O. Box. 84428 , Riyadh 11671 , Saudi Arabia

9. Department of Pharmaceutical Chemistry , College of Pharmacy, University of Mosul , Mosul , 41001 , Iraq

10. Faculty of Biology and Ecology , Yanka Kupala State University of Grodno , 230023 Grodno , Belarus

11. College of technical engineering , The Islamic University , Najaf , Iraq

Abstract

Abstract In today’s world, wound healing is a growing serious problem for clinical institutes. In this study, nanofibrous scaffolds were prepared using polyurethane as a mat scaffold. Also, by immersing curcumin as an antibacterial component another scaffold was fabricated using the electrospinning technique. The obtained scaffolds were characterized by means of scanning electron microscopy, tensile analysis, porosity, and water vapor transmission rate. MTT and DAPI staining were used to prove the biocompatibility and cell attachment of the nanofibers. The curcumin incorporated into the PU scaffold can stop both the Gram-negative and Gram-positive bacteria activities through direct contact with them. Studies showed that the PU/Curcumin scaffold has considerable ability to play a key role in wound healing applications.

Publisher

Walter de Gruyter GmbH

Subject

Materials Chemistry,Metals and Alloys,Physical and Theoretical Chemistry,Condensed Matter Physics

Link

https://www.degruyter.com/document/doi/10.1515/ijmr-2022-0279/pdf

Reference40 articles.

1. Pankongadisak, P., Sangklin, S., Chuysinuan, P., Suwantong, O., Supaphol, P. The use of electrospun curcumin-loaded poly(L-lactic acid) fiber mats as wound dressing materials. J. Drug Deliv. Sci. Technol. 2019, 53, 101121. https://doi.org/10.1016/j.jddst.2019.06.018.

2. Jiang, T., Ghosh, R., Charcosset, C. In vitro anti-inflammatory activity of silymarin/hydroxyapatite/chitosan nanocomposites and its cytotoxic effect using brine shrimp lethality assay. J. Popul. Ther. Clin. Pharmacol. 2021, 112, 419–430. https://doi.org/10.1016/j.tifs.2021.04.015.

3. Esmaeili, E., Eslami-Arshaghi, T., Hosseinzadeh, S., Elahirad, E., Jamalpoor, Z., Hatamie, S., Soleimani, M. The biomedical potential of cellulose acetate/polyurethane nanofibrous mats containing reduced graphene oxide/silver nanocomposites and curcumin: antimicrobial performance and cutaneous wound healing. Int. J. Biol. Macromol. 2020, 152, 418–427. https://doi.org/10.1016/j.ijbiomac.2020.02.295.

4. Thu, H.-E., Zulfakar, M. H., Ng, S.-F. Alginate based bilayer hydrocolloid films as potential slow-release modern wound dressing. Int. J. Pharm. 2012, 434, 375–383. https://doi.org/10.1016/j.ijpharm.2012.05.044.

5. Percival, N. J. Classification of wounds and their management. Surgery 2002, 20, 114–117. https://doi.org/10.1383/surg.20.5.114.14626.

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