Sexual precocity in the setting of parental use of a compounded testosterone cream: case report and review of the literature
Author:
Affiliation:
1. Rutgers Robert Wood Johnson Medical School , Piscataway , NJ , USA
2. Division of Pediatric Endocrinology , Rutgers Robert Wood Johnson Medical School , New Brunswick , NJ , USA
Abstract
Publisher
Walter de Gruyter GmbH
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism,Pediatrics, Perinatology and Child Health
Link
https://www.degruyter.com/document/doi/10.1515/jpem-2022-0521/pdf
Reference11 articles.
1. Bhasin, S, Brito, JP, Cunningham, GR, Hayes, FJ, Hodis, HN, Matsumoto, AM, et al.. Testosterone therapy in men with hypogonadism: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 2018;103:1715–44. https://doi.org/10.1210/jc.2018-00229.
2. Handelsman, DJ. Global trends in testosterone prescribing, 2000–2011: expanding the spectrum of prescription drug misuse. Med J Aust 2013;199:548–51. https://doi.org/10.5694/mja13.10111.
3. Voelker, R. Children’s exposure to testosterone gel spurs FDA to order boxed label warning. JAMA 2009;301:2428. https://doi.org/10.1001/jama.2009.810.
4. Azova, S, Wolfsdorf, J. Precocious sexual development in a male toddler caused by unrecognized transdermal exposure to testosterone: case report and review of the literature. J Pediatr Endocrinol Metab 2021;34:675–8. https://doi.org/10.1515/jpem-2020-0616.
5. Sanderson, E, Abraham, MB, Joseph, J, Boyder, C, Zhang, R, Dedic, D, et al.. Variable persistence of serum testosterone in infants and children exposed to topical testosterone. J Paediatr Child Health 2020;56:1464–7. https://doi.org/10.1111/jpc.14795.
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