Concept of Phase Cycling in Pulsed Magnetic Resonance Using Sinusoidal Magnetic Field Modulation

Author:

Tseytlin Mark123

Affiliation:

1. Department of Biochemistry, School of Medicine, West Virginia University, Morgantown, West Virginia, United States of America

2. Center for EPR Imaging In Vivo Physiology, Department of Radiation and Cellular Oncology, University of Chicago, IL, United States of America

3. In vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown, WV, United States of America

Abstract

Abstract In conventional pulsed magnetic resonance suppression of unwanted signals is achieved by changing pulse phases with respect to the reference signal and spin magnetization phase. This method is called phase cycling. An alternative approach is suggested to separate the unwanted signals from the spin echo by using magnetic field modulation. Precession frequency of the spins, and therefore phases of free indication decays and echo signals, can be controlled by the selection of modulation parameters. This enables phase cycling. Since the signal is detected in the presence of the changing magnetic field, which drives spin precession, the echo signal is frequency-modulated. Numerical transformation into an accelerating reference frame associated with the Larmor frequency restores the signal to a form that would have been observed in the absence of modulation. The suggested phase cycling method is analyzed in detail for the two pulse spin echo case.

Publisher

Walter de Gruyter GmbH

Subject

Physical and Theoretical Chemistry

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