Promotive Effects of the Dietary Organic Germanium Poly-trans-[(2-carboxyethyl) germasesquioxane] (Ge-132) on the Secretion and Antioxidative Activity of Bile in Rodents

Author:

Nakamura Takashi12,Nagura Taizo3,Akiba Mitsuo2,Sato Katsuyuki2,Tokuji Yoshihiko4,Ohnishi Masao14,Osada Kyoichi15

Affiliation:

1. The United Graduate School of Agricultural Sciences, Iwate University

2. Asai Germanium Research Institute Co., Ltd.

3. Nippon Beet Sugar MFG., Co., Ltd.

4. Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine

5. Department of Agricultural Chemistry, Meiji University

Publisher

Pharmaceutical Society of Japan

Subject

Health, Toxicology and Mutagenesis,Toxicology

Reference27 articles.

1. Crystal structure of "carboxyethylgermanium sesquioxide"

2. 2) Sugiya, Y., Sakamaki, S., Sugita, T., Abo, Y. and Satoh, H. (1986) Subacute oral toxicity of carboxyethylgermanium sesquioxide (Ge-132) in rats. Ouyou Yakuri, 31, 1181-1190 (in Japanese).

3. 3) Miyao, K. and Tanaka, N. (1988) Carboxyethylgermanium sesquioxide and related organogermanium compounds. Drugs of the Future, 13, 441-453.

4. Antitumor effect of the organogermanium compound Ge-132 on the Lewis lung carcinoma (3LL) in C57Bl/6 (B6) mice.

5. 5) Aso, H., Suzuki, F., Ebina, T. and Ishida, N. (1989) Antiviral activity of caboxyethylgermanium sesquioxide (Ge-132) in mice infected with influenza virus. J. Biol. Response Mod., 8, 180-189.

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