Design, Synthesis and Biological Evaluation of a Novel Series of Potent, Orally Active Adenosine A<SUB>1</SUB> Receptor Antagonists with High Blood-Brain Barrier Permeability-Reference-Cited by-同舟云学术

Design, Synthesis and Biological Evaluation of a Novel Series of Potent, Orally Active Adenosine A₁ Receptor Antagonists with High Blood-Brain Barrier Permeability

Published:2001 Issue:8 Volume:49 Page:988-998
ISSN:0009-2363
Container-title:Chemical and Pharmaceutical Bulletin
language:en
Short-container-title:CHEMICAL & PHARMACEUTICAL BULLETIN

Author:

KURODA Satoru¹,TAKAMURA Fujiko¹,TENDA Yoshiyuki¹,ITANI Hiromichi¹,TOMISHIMA Yasuyo¹,AKAHANE Atsushi¹,SAKANE Kazuo¹

Affiliation:

1. Medicinal Chemistry Research Laboratories, Fujisawa Pharmaceutical Co., Ltd.

Publisher

Pharmaceutical Society of Japan

Subject

Drug Discovery,General Chemistry,General Medicine

Link

https://www.jstage.jst.go.jp/article/cpb/49/8/49_8_988/_pdf

Reference34 articles.

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3. 2) a) Fredholm B.B., Abbracchio M.P., Burnstock G., Daly J.W., Harden K., Jacobson K.A., Leff P., Williams M., Pharmacol. Rev., 46, 143-156 (1994)

4. b) Collis M.G., Hourani S.M.O., Trends. Pharmacol. Sci., 14, 360-366 (1993).

5. 3) a) Stehle J.H., Rivkees S.A., Lee J.J., Weaver D.R., Deeds J.D., Reppert S.M., Mol. Endocr., 6, 384-393 (1992)

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