Antioxidant and Prooxidant Effects of Thymoquinone and Its Hydroquinone Metabolite-Reference-Cited by-同舟云学术

Antioxidant and Prooxidant Effects of Thymoquinone and Its Hydroquinone Metabolite

Published:2022-09-01 Issue:9 Volume:45 Page:1389-1393
ISSN:0918-6158
Container-title:Biological and Pharmaceutical Bulletin
language:en
Short-container-title:Biological & Pharmaceutical Bulletin

Author:

Mizuno Mirei¹,Fukuhara Kiyoshi¹

Affiliation:

1. Division of Organic and Medicinal Chemistry, School of Pharmacy, Showa University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Link

https://www.jstage.jst.go.jp/article/bpb/45/9/45_b22-00199/_pdf

Reference14 articles.

1. 1) Gali-Muhtasib H, Diab-Assaf M, Boltze C, Al-Hmaira J, Hartig R, Roessner A, Schneider-Stock R. Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism. Int. J. Oncol., 25, 857–866 (2004).

2. 2) Mansour MA, Nagi MN, El-Khatib AS, Al-Bekairi AM. Effects of thymoquinone on antioxidant enzyme activities, lipid peroxidation and DT-diaphorase in different tissues of mice: a possible mechanism of action. Cell Biochem. Funct., 20, 143–151 (2002).

3. 3) Mahmoud YK, Abdelrazek HMA. Cancer: Thymoquinone antioxidant/pro-oxidant effect as potential anticancer remedy. Biomed. Pharmacother., 115, 108783 (2019).

4. 4) Zubair H, Khan HY, Sohail A, Azim S, Ullah MF, Ahmad A, Sarkar FH, Hadi SM. Redox cycling of endogenous copper by thymoquinone leads to ROS-mediated DNA breakage and consequent cell death: putative anticancer mechanism of antioxidants. Cell Death Dis., 4, e660 (2013).

5. 5) Bolton JL, Trush MA, Penning TM, Dryhurst G, Monks TJ. Role of quinones in toxicology. Chem. Res. Toxicol., 13, 135–160 (2000).

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2. Antioxidant Thymoquinone and Its Potential in the Treatment of Neurological Diseases;Antioxidants;2023-02-09