Conformational Analysis of the NMDA Receptor Antagonist (1S,2R)-1-Phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PPDC) Designed by a Novel Conformational Restriction Method Based on the Structural Feature of Cyclopropane Ring.-Reference-Cited by-同舟云学术

Conformational Analysis of the NMDA Receptor Antagonist (1S,2R)-1-Phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PPDC) Designed by a Novel Conformational Restriction Method Based on the Structural Feature of Cyclopropane Ring.

Published:2002 Issue:7 Volume:50 Page:966-968
ISSN:0009-2363
Container-title:Chemical and Pharmaceutical Bulletin
language:en
Short-container-title:CHEMICAL & PHARMACEUTICAL BULLETIN

Author:

Ono Sizuka¹,Ogawa Kiyoshi²,Yamashita Kanako²,Yamamoto Tamotsu²,Kazuta Yuji¹,Matsuda Akira¹,Shuto Satoshi¹

Affiliation:

1. Graduate School of Pharmaceutical Sciences, Hokkaido University

2. Institute of Life Science Research, Asahi Chemical Co., Ltd.

Publisher

Pharmaceutical Society of Japan

Subject

Drug Discovery,General Chemistry,General Medicine

Link

http://www.jstage.jst.go.jp/article/cpb/50/7/50_7_966/_pdf

Reference37 articles.

1. 1) Silverman R. B., “The Organic Chemistry of Drug Design and Drug Action,” Academic Press, San Diego, 1992.

2. 2) Kozikowski A. (ed.), “Drug Design for Neuroscience,” Raven Press, New York, 1993.

3. 3) Wermuth C. G. (ed.), “The Practice of Medicinal Chemistry,” Academic Press, San Diego, 1996.

4. Syntheses and Conformational Analyses of Glutamate Analogs: 2-(2-Carboxy-3-substituted-cyclopropyl)glycines as Useful Probes for Excitatory Amino Acid Receptors

5. 5) For example see: Armstrong D. P., Cannon J. G., J. Med. Chem., 13, 1037—1039 (1970).

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Potent and reversible open-channel blocker of NMDA receptor derived from dizocilpine with enhanced membrane-to-channel inhibition;Biomedicine & Pharmacotherapy;2024-09

2. Potent and reversible open-channel blocker of NMDA receptor derived from dizocilpine with enhanced membrane-to-channel inhibition;2024-04-17

3. Synthesis and biological activity of cyclopropyl Δ7-dafachronic acids as DAF-12 receptor ligands;Organic & Biomolecular Chemistry;2021

4. Medicinal Chemical Studies Based on the Theoretical Design of Bioactive Compounds;YAKUGAKU ZASSHI;2020-03-01

5. Synthesis and biological evaluation of bromophenol derivatives with cyclopropyl moiety: Ring opening of cyclopropane with monoester;Bioorganic Chemistry;2019-08