Application of the PKCYP-test in Cases of Altered CYP1A2 for Multiple CYP Systems in Rat Models of Disease.
Author:
Affiliation:
1. Department of Pharmaceutics, Kyoritsu College of Pharmacy
2. Department of Practical Pharmacy, Kyoritsu College of Pharmacy
3. The Organization for Pharmaceutical Safety and Research
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
http://www.jstage.jst.go.jp/article/bpb/24/9/24_9_1037/_pdf
Reference22 articles.
1. Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data
2. A Simplified Diagnostic Approach for Estimating in vivo Hepatic Drug Clearance. Its Preliminary Application for the Drug Caffeine, Using CYP1A Probe in a Rat Model.
3. Role of cytochrome P450 IA2 in acetanilide 4-hydroxylation as determined with cDNA expression and monoclonal antibodies
Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Prediction of Theophylline Clearance in CCl4-treated Rats Using in vivo CYP1A2 and CYP3A2 Contents Assessed with the PKCYP Test;Drug Metabolism and Pharmacokinetics;2005
2. Application of the PKCYP Test to Predict Caffeine Clearance Mediated by CYP1A2 in a Rat Acute Liver Injury Model;Drug Metabolism and Pharmacokinetics;2003
3. Simultaneous Assessment of the In Vivo Amount of CYP1A2 and CYP3A2 by the PKCYP-test Using Theophylline in Rats;Drug Metabolism and Pharmacokinetics;2002
4. Application of the PKCYP-test to Predict the Amount of in Vivo CYP2C11 Using Tolbutamide as a Probe.;Biological and Pharmaceutical Bulletin;2001
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