Application of the PKCYP-test to Predict the Amount of in Vivo CYP2C11 Using Tolbutamide as a Probe.
Author:
Affiliation:
1. Department of Pharmaceutics, Kyoritsu College of Pharmacy
2. Department of Practical Pharmacy, Kyoritsu College of Pharmacy
3. The Organization for Pharmaceutical Safety and Research
4. Cancer Institute Hospital
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
http://www.jstage.jst.go.jp/article/bpb/24/11/24_11_1305/_pdf
Reference23 articles.
1. Phenotyping of drug-metabolizing enzymes in adults: a review of in-vivo cytochrome P450 phenotyping probes
2. Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data
3. A Simplified Diagnostic Approach for Estimating in vivo Hepatic Drug Clearance. Its Preliminary Application for the Drug Caffeine, Using CYP1A Probe in a Rat Model.
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