Discovery of 1,3-Disubstituted 2,5-Diketopiperazine Derivatives as Potent Class I HDACs Inhibitors-Reference-Cited by-同舟云学术

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Discovery of 1,3-Disubstituted 2,5-Diketopiperazine Derivatives as Potent Class I HDACs Inhibitors

Published:2020-05-01 Issue:5 Volume:68 Page:466-472
ISSN:0009-2363
Container-title:Chemical and Pharmaceutical Bulletin
language:en
Short-container-title:CHEMICAL & PHARMACEUTICAL BULLETIN

Author:

Gong Guoliang¹,Qi Jianzhao¹,Lv Ye²,Dong Shuai³,Cao Chenyu¹,Li Ding¹,Zhao Ru²,Li Zhen²,Chen Xin¹

Affiliation:

1. Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University

2. The Second Affiliated Hospital of Xi’an Jiaotong University

3. Key Laboratory of Tropical Biological Resources, Ministry of Education

Publisher

Pharmaceutical Society of Japan

Subject

Drug Discovery,General Chemistry,General Medicine

Link

https://www.jstage.jst.go.jp/article/cpb/68/5/68_c20-00056/_pdf

Reference25 articles.

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2. 2) Falkenberg K. J., Johnstone R. W., Nat. Rev. Drug Discov., 13, 673–691 (2014).

3. 3) Weichert W., Cancer Lett., 280, 168–176 (2009).

4. 4) Khan O., La Thangue N. B., Immunol. Cell Biol., 90, 85–94 (2012).

5. 5) Gammoh N., Lam D., Puente C., Ganley I., Marks P. A., Jiang X., Proc. Natl. Acad. Sci. U.S.A., 109, 6561–6565 (2012).

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1. Multimechanism biological profiling of tetrahydro-β-carboline analogues as selective HDAC6 inhibitors for the treatment of Alzheimer's disease;European Journal of Medicinal Chemistry;2024-09

2. 2,5-Diketopiperazines (DKPs): Promising Scaffolds for Anticancer Agents;Current Pharmaceutical Design;2024-03

3. Design, synthesis and antiproliferative evaluation of tetrahydro-β-carboline histone deacetylase inhibitors bearing an aliphatic chain linker;RSC Advances;2024

4. Tetrahydro-β-carboline derivatives as potent histone deacetylase 6 inhibitors with broad-spectrum antiproliferative activity;European Journal of Medicinal Chemistry;2023-11

5. Design, synthesis and antiproliferative activity of ACY-1215 analogs as potent selective histone deacetylases 6 inhibitors;Medicinal Chemistry Research;2023-09-20

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