Pharmacokinetics/Pharmacodynamics Analysis of the Relationship between the in Vivo Micturition Pressure and Receptor Occupancy of (R)-Oxybutynin and Its Metabolite in Rats-Reference-Cited by-同舟云学术

Pharmacokinetics/Pharmacodynamics Analysis of the Relationship between the in Vivo Micturition Pressure and Receptor Occupancy of (R)-Oxybutynin and Its Metabolite in Rats

Published:2007 Issue:5 Volume:30 Page:955-962
ISSN:0918-6158
Container-title:Biological and Pharmaceutical Bulletin
language:en
Short-container-title:Biol. Pharm. Bull.

Author:

Mizushima Haruhi¹,Kinoshita Kazuya²,Abe Koji³,Ishizuka Hitoshi¹,Yamada Yasuhiko⁴

Affiliation:

1. Clinical Pharmacology and Biostatistics Department, Sankyo Co., Ltd.

2. Pharmacodynamics Research Laboratories, Sankyo Co., Ltd.

3. Drug Metabolism and Pharmacokinetics Research Laboratories, Sankyo Co., Ltd.

4. Department of Clinical Evaluation of Drug Efficacy, School of Pharmacy, Tokyo University of Pharmacy and Life Science

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Link

http://www.jstage.jst.go.jp/article/bpb/30/5/30_5_955/_pdf

Reference27 articles.

1. Prospective Randomized Controlled Trial of Extended-Release Oxybutynin Chloride and Tolterodine Tartrate in the Treatment of Overactive Bladder: Results of the OBJECT Study

2. Prospective, Randomized, Double-Blind Study of the Efficacy and Tolerability of the Extended-Release Formulations of Oxybutynin and Tolterodine for Overactive Bladder: Results of the OPERA Trial

3. Muscarinic receptors in the bladder: from basic research to therapeutics

4. Tolterodine – a new bladder-selective antimuscarinic agent

5. Human Muscarinic Receptor Binding Characteristics of Antimuscarinic Agents to Treat Overactive Bladder

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