Bootstrap Re-sampling Technique to Evaluate the Optimal Formulation of Theophylline Tablets Predicted by Non-linear Response Surface Method Incorporating Multivariate Spline Interpolation
Author:
Affiliation:
1. Pharmaceutical Technology Research Laboratories, Daiichi Pharmaceutical Co., Ltd.
2. Research and Development Headquarters, Yamatake Corporation
3. Department of Pharmaceutics, Hoshi University
Publisher
Pharmaceutical Society of Japan
Subject
Drug Discovery,General Chemistry,General Medicine
Link
http://www.jstage.jst.go.jp/article/cpb/55/4/55_4_586/_pdf
Reference21 articles.
1. 1) ICH draft guideline, “Pharmaceutical Development Q8,” version 4.3, November 2005.
2. Identification of critical formulation and processing variables for metoprolol tartrate extended-release (ER) matrix tablets1This manuscript represents the personal opinions of the authors and does not necessarily represent the views or policies of the FDA.1
3. Evaluation and simultaneous optimization of some pellets characteristics using a 33 factorial design and the desirability function
4. Optimization of Sustained-Release Propranolol Dosage form Using Factorial Design and Response Surface Methodology
5. Optimization of Methacrylic Acid Ester Copolymers Blends as Controlled Release Coatings Using Response Surface Methodology
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