Inhibition of Methotrexate Uptake via Organic Anion Transporters OAT1 and OAT3 by Glucuronides of Nonsteroidal Anti-inflammatory Drugs
Author:
Affiliation:
1. Department of Pharmacy, Faculty of Pharmacy, Kindai University
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/40/6/40_b16-00970/_pdf
Reference38 articles.
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2. 2) Thyss A, Milano G, Kubar J, Namer M, Schneider M. Clinical and pharmacokinetic evidence of a life-threatening interaction between methotrexate and ketoprofen. Lancet, 327, 256–258 (1986).
3. 3) Cassano WF. Serious methotrexate toxicity caused by interaction with ibuprofen. Am. J. Pediatr. Hematol. Oncol., 11, 481–482 (1989).
4. 4) Singh RR, Malaviya AN, Pandey JN, Guleria JS. Fatal interaction between methotrexate and naproxen. Lancet, 1, 1390 (1986).
5. 5) Tracy TS, Krohn K, Jones DR, Bradley JD, Hall SD, Brater DC. The effects of a salicylate, ibuprofen, and naproxen on the disposition of methotrexate in patients with rheumatoid arthritis. Eur. J. Clin. Pharmacol., 42, 121–125 (1992).
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