NQ-Y15 Inhibits the Calcium Mobilization by Elevation of Cyclic AMP in Rat Platelets.
Author:
Affiliation:
1. College of Pharmacy, Seoul National University
2. Department of Environmental Engineering, Sunmoon University
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
http://www.jstage.jst.go.jp/article/bpb/24/5/24_5_480/_pdf
Reference34 articles.
1. Mechanisms of platelet activation: Thromboxane A2 as an amplifying signal for other agonists
2. Arachidonic acid stimulates the formation of 1,2-diacylglycerol and phosphatidic acid in human platelets. Degree of phospholipase C activation correlates with protein phosphorylation, platelet shape change, serotonin release, and aggregation.
3. Inositol 1,4,5-triphosphate-induced granule secretion in platelets. Evidence that the activation of phospholipase C mediated by platelet thromboxane receptors involves a guanine nucleotide binding protein-dependent mechanism distinct from that of thrombin.
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