Arachidonic acid stimulates the formation of 1,2-diacylglycerol and phosphatidic acid in human platelets. Degree of phospholipase C activation correlates with protein phosphorylation, platelet shape change, serotonin release, and aggregation.-Reference-Cited by-同舟云学术

Arachidonic acid stimulates the formation of 1,2-diacylglycerol and phosphatidic acid in human platelets. Degree of phospholipase C activation correlates with protein phosphorylation, platelet shape change, serotonin release, and aggregation.

Published:1983-09 Issue:18 Volume:258 Page:11236-11242
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Siess W,Siegel F L,Lapetina E G

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference49 articles.

1. Stimulation of phosphatidic acid production in platelets precedes the formation of arachidonate and parallels the release of serotonin

2. Selective release of archidonic acid from the phospholipids of human platelets in response to thrombin.

3. The phosphatidylinositol cycle and the regulation of arachidonic acid production

4. Phospholipid Metabolism in Stimulated Human Platelets

5. Effect of ADP-induced Shape Change on Incorporation of32P into Platelet Phosphatidic Acid and Mono-, Di- and Triphosphatidyl Inositol

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