Synthesis and Structure-Activity Relationship of N-Arylrolipram Derivatives as Inhibitors of PDE4 Isozymes.

Author:

KELLER Thomas H.1,BRAY-FRENCH Katharine1,DEMNITZ F.W. Joachim1,MÜLLER Thomas1,POMBO-VILLAR Esteban1,WALKER Christoph1

Affiliation:

1. Respiratory Disease Therapeutic Area, Novartis Horsham Research Center

Publisher

Pharmaceutical Society of Japan

Subject

Drug Discovery,General Chemistry,General Medicine

Reference40 articles.

1. 1) Present address: Universidade Federal de Pernambuco, Departamento de Quimica Fundamental, Cidade Universitária, 50.670-901 Recife-Pe, Brasil.

2. The immunopharmacology of mild asthma☆☆☆★

3. Effectiveness of prophylactic inhaled steroids in childhood asthma: A systematic review of the literature☆☆☆★

4. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC

5. 5) Schudt C., Dent G., Rabe K.F. (eds.), “Phosphodiesterase Inhibitors.” Academic Press, London, 1996.

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