Elucidation of a Structural Basis for the Inhibitor-Driven, p62 (SQSTM1)-Dependent Intracellular Redistribution of cAMP Phosphodiesterase-4A4 (PDE4A4)-Reference-Cited by-同舟云学术

Elucidation of a Structural Basis for the Inhibitor-Driven, p62 (SQSTM1)-Dependent Intracellular Redistribution of cAMP Phosphodiesterase-4A4 (PDE4A4)

Published:2011-04-13 Issue:9 Volume:54 Page:3331-3347
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Day Jonathan P.¹,Lindsay Barbara²,Riddell Tracy¹,Jiang Zhong²,Allcock Robert W.²,Abraham Achamma²,Sookup Sebastian¹,Christian Frank¹,Bogum Jana³,Martin Elisabeth K.²,Rae Robert L.²,Anthony Diana¹,Rosair Georgina M.²,Houslay Daniel M.¹,Huston Elaine¹,Baillie George S.¹,Klussmann Enno³,Houslay Miles D.¹,Adams David R.²

Affiliation:

1. Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, U.K.

2. Department of Chemistry, School of Engineering and Physical Sciences, Heriot-Watt University, Riccarton Campus, Edinburgh EH14 4AS, U.K.

3. Max-Delbrück-Centrum für Molekulare Medizin (MDC), Berlin-Buch, Robert-Rössle-Strasse 10, 13125 Berlin, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm200070e

Reference50 articles.

1. Cyclic AMP-specific PDE4 Phosphodiesterases as Critical Components of Cyclic AMP Signaling

2. PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization

3. Cyclic AMP-dependent Transcriptional Up-regulation of Phosphodiesterase 4D5 in Human Airway Smooth Muscle Cells

4. Structure of two rat genes coding for closely related rolipram-sensitive cAMP phosphodiesterases. Multiple mRNA variants originate from alternative splicing and multiple start sites.

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