Basic Fibroblast Growth Factor Is Essential to Maintain Endothelial Progenitor Cell Phenotype in TR-BME2 Cells

Author:

Sai Yoshimichi12,Nishimura Tomohiro1,Muta Mariko13,Iizasa Hisashi14,Miyata Takashi1,Nakashima Emi1

Affiliation:

1. Division of Pharmaceutics, Faculty of Pharmacy, Keio University

2. Department of Pharmacy, Kanazawa University Hospital

3. Department of Health and Dietetics, Faculty of Medical Health, Teikyo Heisei University

4. Division of Stem Cell Biology, Institute for Genetic Medicine, Hokkaido University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference30 articles.

1. 1) Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, Li T, Witzenbichler B, Schatteman G, Isner JM. Isolation of putative progenitor endothelial cells for angiogenesis. Science, 275, 964–967 (1997).

2. 2) Miyata T, Iizasa H, Sai Y, Fujii J, Terasaki T, Nakashima E. Platelet-derived growth factor-BB (PDGF-BB) induces differentiation of bone marrow endothelial progenitor cell-derived cell line TR-BME2 into mural cells, and changes the phenotype. J. Cell. Physiol., 204, 948–955 (2005).

3. 3) Crosby JR, Kaminski WE, Schatteman G, Martin PJ, Raines EW, Seifert RA, Bowen-Pope DF. Endothelial cells of hematopoietic origin make a significant contribution to adult blood vessel formation. Circ. Res., 87, 728–730 (2000).

4. 4) Enarsson M, Erlandsson A, Larsson H, Forsberg-Nilsson K. Extracellular signal-regulated protein kinase signaling is uncoupled from initial differentiation of central nervous system stem cells to neurons. Mol. Cancer Res., 1, 147–154 (2002).

5. 5) Kazemi S, Wenzel D, Kolossov E, Lenka N, Raible A, Sasse P, Hescheler J, Addicks K, Fleischmann BK, Bloch W. Differential role of bFGF and VEGF for vasculogenesis. Cell. Physiol. Biochem., 12, 55–62 (2002).

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