Ordinary and Activated Osteoplastic Materials

Abstract

Osteoplastic materials are highly required medical devices for bone defects substitution and filling the areas of bone tissue atrophy. Based on analysis of modern groups of osteoplastic materials, features of their composition, mechanisms of biological action, and indications for clinical use, the applied classification which divides the medical items into ordinary and activated categories is proposed. The main differential criterion is the presence of certain biologically active components in the material composition: growth factors, cells or gene constructions encoding growth factors that are standardized by qualitative and quantitative parameters. Pronounced osteoinductive and (or) osteogenic properties of activated osteoplastic materials enable counting on their effectiveness in replacement of large bone defects.