Bioactivation of Morphine in Human Liver: Isolation and Identification of Morphinone, a Toxic Metabolite
Author:
Affiliation:
1. Faculty of Pharmaceutical Sciences, Fukuoka University
2. Faculty of Pharmaceutical Sciences, Okayama University
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
http://www.jstage.jst.go.jp/article/bpb/28/7/28_7_1275/_pdf
Reference20 articles.
1. Protective effect of sulfhydryl compounds on acute toxicity of morphinone
2. Morphine metabolism revisited: I. metabolic activation of morphine to a reactive species in rats
3. Purification and characterization of guinea pig liver morphine 6-dehydrogenase.
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