Sphingo-guanidines and their use as inhibitors of sphingosine kinase (WO2010078247)
Author:
Publisher
Informa Healthcare
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1517/13543776.2011.573787
Reference23 articles.
1. Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
2. Sphingosine Kinase: Biochemical and Cellular Regulation and Role in Disease
3. Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases
4. Sphingosine-1-phosphate: an enigmatic signalling lipid
5. Sphingosine and its methylated derivative N,N-dimethylsphingosine (DMS) induce apoptosis in a variety of human cancer cell lines
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2. Therapeutic Potential of SphK1 Inhibitors Based on Abnormal Expression of SphK1 in Inflammatory Immune Related-Diseases;Frontiers in Pharmacology;2021-10-19
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4. Rational design of SphK inhibitors using crystal structures aided by computer;European Journal of Medicinal Chemistry;2021-03
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