Dawn of Aurora kinase inhibitors as anticancer drugs
Author:
Publisher
Informa Healthcare
Subject
Pharmacology (medical),Pharmacology,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1517/13543784.13.9.1199
Reference5 articles.
1. VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo
2. Cotreatment with 17-Allylamino-Demethoxygeldanamycin and FLT-3 Kinase Inhibitor PKC412 Is Highly Effective against Human Acute Myelogenous Leukemia Cells with Mutant FLT-3
3. The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint
4. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores
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1. Aurora kinase inhibitor VX-680 enhances sensitivity of esophageal squamous cell carcinoma cells to cisplatin chemotherapy;Anti-Cancer Drugs;2021-05-19
2. Aurora kinase inhibitor VX‑680 suppresses the proliferation and migration of HUVECs and angiogenesis;Molecular Medicine Reports;2019-02-27
3. Influence of a novel histone deacetylase inhibitor panobinostat (LBH589) on the growth of ovarian cancer;Journal of Ovarian Research;2016-09-15
4. Aurora Kinases as Druggable Targets in Pediatric Leukemia: Heterogeneity in Target Modulation Activities and Cytotoxicity by Diverse Novel Therapeutic Agents;PLoS ONE;2014-07-21
5. CDKN1A-mediated responsiveness ofMLL-AF4-positive acute lymphoblastic leukemia to Aurora kinase-A inhibitors;International Journal of Cancer;2014-01-13
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