Targeting mast cells
Author:
Publisher
Informa Healthcare
Subject
Pharmacology (medical),Pharmacology,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1517/13543784.13.7.739
Reference8 articles.
1. Mast Cell-IgE-and Mast Cell-Structural Cell Interactions in Allergic Airway Disease
2. Toll-Like Receptor-Mediated Activation of Mast Cells: Implications for Allergic Disease?
3. Inhibitors of Tryptase as Mast Cell-Stabilizing Agents in the Human Airways: Effects of Tryptase and Other Agonists of Proteinase-Activated Receptor 2 on Histamine Release
4. Inhibition of mast cell tryptase by inhaled APC 366 attenuates allergen-induced late-phase airway obstruction in asthma
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1. Heparin makes differences: a molecular dynamics simulation study on the human βII-tryptase monomer;Molecular BioSystems;2015
2. A β-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity;Bioorganic & Medicinal Chemistry Letters;2012-02
3. Structure-based design, synthesis, and profiling of a β-tryptase inhibitor with a spiro-piperidineamide scaffold, benzylamine P1 group, and a substituted indole P4 group;MedChemComm;2011
4. Inflammation in Respiratory Allergy Treated by Sublingual Immunotherapy;European Journal of Inflammation;2009-09
5. Structure based design of 4-(3-aminomethylphenyl)piperidinyl-1-amides: novel, potent, selective, and orally bioavailable inhibitors of βII tryptase;Bioorganic & Medicinal Chemistry;2005-04
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