Using pharmacokinetic/pharmacodynamic modelling in safety pharmacology to better define safety margins: a regional workshop of the Safety Pharmacology Society-Reference-Cited by-同舟云学术

Using pharmacokinetic/pharmacodynamic modelling in safety pharmacology to better define safety margins: a regional workshop of the Safety Pharmacology Society

Published:2007-07 Issue:4 Volume:6 Page:465-471
ISSN:1474-0338
Container-title:Expert Opinion on Drug Safety
language:en
Short-container-title:Expert Opinion on Drug Safety

Author:

Cavero Icilio

Publisher

Informa Healthcare

Subject

Pharmacology (medical),General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.1517/14740338.6.4.465

Reference12 articles.

1. Mechanism-Based Pharmacokinetic-Pharmacodynamic Modeling: Biophase Distribution, Receptor Theory, and Dynamical Systems Analysis

2. Pharmacokinetic/Pharmacodynamic Modeling in Drug Development

3. Operational models of pharmacological agonism

4. A pharmacokinetic-pharmacodynamic model for the quantitative prediction of dofetilide clinical QT prolongation from human ether-a-go-go-related gene current inhibition data

5. A novel approach to data processing of the QT interval response in the conscious telemetered beagle dog

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