The role of concentration−effect relationships in the assessment of QTcinterval prolongation
Author:
Affiliation:
1. Medicines Discovery and Development; GlaxoSmithKline; Uxbridge UK
2. Department of Pharmacology; School of Life and Medical Sciences; UCL; London UK
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.12443/fullpdf
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4. Performance characteristics for some typical QT study designs under the ICH E-14 guidance;Hutmacher;J Clin Pharmacol,2008
5. Does low-dose droperidol administration increase the risk of drug-induced QT prolongation and torsade de pointes in the general surgical population?;Nuttall;Anesthesiology,2007
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