RANKL blockade improves efficacy of PD1-PD-L1 blockade or dual PD1-PD-L1 and CTLA4 blockade in mouse models of cancer

Author:

Ahern Elizabeth12,Harjunpää Heidi34,O'Donnell Jake S.134,Allen Stacey3,Dougall William C.15,Teng Michele W. L.34,Smyth Mark J.14

Affiliation:

1. Department of Immunology, Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia

2. Division of Cancer Care Services, Medical Oncology, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia

3. Department of Immunology, Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia

4. Faculty of Medicine, University of Queensland, Herston, Queensland, Australia

5. Department of Immunology, Immuno-oncology Discovery Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia

Funder

National Health and Medical Research Council (NHMRC)

Cancer Council Queensland

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

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