Efficacy, pharmacokinetic and pharmacodynamic evaluation of apaziquone in the treatment of non-muscle invasive bladder cancer-Reference-Cited by-同舟云学术

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Efficacy, pharmacokinetic and pharmacodynamic evaluation of apaziquone in the treatment of non-muscle invasive bladder cancer

Published:2017-07-03 Issue:7 Volume:13 Page:783-791
ISSN:1742-5255
Container-title:Expert Opinion on Drug Metabolism & Toxicology
language:en
Short-container-title:Expert Opinion on Drug Metabolism & Toxicology

Author:

Phillips R. M.¹²,Hendriks H. R.³,Sweeney J. B.¹²,Reddy G.⁴,Peters G. J.⁵

Affiliation:

1. Department of Pharmacy, University of Huddersfield, Huddersfield, UK

2. Department of Chemical Sciences, University of Huddersfield, UK

3. Hendriks Pharmaceutical Consulting, Purmerend, The Netherlands

4. Spectrum Pharmaceuticals Inc, Irvine, CA, USA

5. Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands

Publisher

Informa UK Limited

Subject

Pharmacology,Toxicology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/17425255.2017.1341490

Reference72 articles.

1. Mitomycin analogs I. Indoloquinones as (potential) bisalkylating agents

2. EO9: A novel bioreductive alkylating indoloquinone with preferential solid tumour activity and lack of bone marrow toxicity in preclinical models

3. Targeting the hypoxic fraction of tumours using hypoxia-activated prodrugs

4. Hypoxia-activated prodrugs: paths forward in the era of personalised medicine

5. Evaluation of a novel in vitro assay for assessing drug penetration into avascular regions of tumours

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