Pediatric drug safety signal detection of non-chemotherapy drug-induced neutropenia and agranulocytosis using electronic healthcare records

Author:

Wei Ran1ORCID,Jia Lu-Lu1,Yu Yun-Cui1,Nie Xiao-Lu2,Song Zi-Yang3,Fan Duan-Fang1,Xie Yue-Feng4,Peng Xiao-Xia2,Zhao Zhi-Gang5,Wang Xiao-Ling13

Affiliation:

1. Clinical Research Center, National Center for Children‘s Health, Beijing Children’s Hospital, Capital Medical University, Beijing, China

2. Center for Clinical Epidemiology and Evidence-Based Medicine, National Center for Children‘s Health, Beijing Children’s Hospital, Capital Medical University, Beijing, China

3. Department of Pharmacy, National Center for Children‘s Health, Beijing Children’s Hospital, Capital Medical University, Beijing, China

4. Information Center, National Center for Children‘s Health, Beijing Children’s Hospital, Capital Medical University, Beijing, China

5. Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

Funder

National Major Scientific and Technological Special Project

National Natural Science Foundation of China

Publisher

Informa UK Limited

Subject

Pharmacology (medical),General Medicine

Reference29 articles.

1. Pediatric Drug Safety Signal Detection: A New Drug–Event Reference Set for Performance Testing of Data-Mining Methods and Systems

2. Unlicensed and Off-Label Drug Use

3. Pharmacovigilance evaluation of the relationship between impaired glucose metabolism and BCR-ABL inhibitor use by using an adverse drug event reporting database

4. Pharmacovigilance: methods, recent developments and future perspectives

5. Overview of neutropenia in children and adolescents [2019 Feb 15; cited 2019 Mar 24]. Available from: https://www.uptodate.com/contents/zh-Hans/overview-of-neutropenia-in-children-and-adolescents?search=neutropenia&source=search_result&selectedTitle=2~150&usage_type=default&display_rank=2

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