Metabolic activation ofo-phenylphenol to a major cytotoxic metabolite, phenylhydroquinone: role of human CYP1A2 and rat CYP2C11/CYP2E1-Reference-Cited by-同舟云学术

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Metabolic activation ofo-phenylphenol to a major cytotoxic metabolite, phenylhydroquinone: role of human CYP1A2 and rat CYP2C11/CYP2E1

Published:2000-01 Issue:10 Volume:30 Page:1005-1017
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Ozawa S.,Ohta K.,Miyajima A.,Kurebayashi H.,Sunouchi M.,Shimizu M.,Murayama N.,Matsumoto Y.,Fukuoka M.,Ohno Y.

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.1080/00498250050200159

Reference18 articles.

1. Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites

2. Oxygen and Xenobiotic Reductase Activities of Cytochrome P450

3. Genotoxic effects of the o-phenylphenol metabolites phenylhydroquinone and phenylbenzoquinone in V79 cells

4. Regioselective hydroxylation of debrisoquine by cytochrome P4502D6: implications for active site modelling

5. The effects of orthophenylphenol, tris(2,3-dichloropropyl) phosphate, and cyclophosphamide on the immune system and host susceptibility of mice following subchronic exposure

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