Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity
Author:
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1080/00498250903000255
Reference67 articles.
1. A unified theory of enzyme kinetics based upon the systematic analysis of the variations of kcat, KM, and kcat/KM and the relevant ΔG0≠ values—possible implications in chemotherapy and biotechnology
2. The relation between the divergence of sequence and structure in proteins.
3. Human Drug Metabolism
4. In Silico Methods for Predicting Ligand Binding Determinants of Cytochromes P450
Cited by 25 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Identification and in silico prediction of metabolites of tebufenozide derivatives by major human cytochrome P450 isoforms;Bioorganic & Medicinal Chemistry;2020-05
2. Mechanistic Insights into the Directing Effect of Thr303 in Ethanol Oxidation by Cytochrome P450 2E1;ACS Catalysis;2019-04-18
3. Combinatorial biosynthesis of small molecules in plants: Engineering strategies and tools;Methods in Enzymology;2019
4. Prediction of Human Cytochrome P450 Inhibition Using a Multitask Deep Autoencoder Neural Network;Molecular Pharmaceutics;2018-05-18
5. Transient Expression of Human Cytochrome P450s 2D6 and 3A4 in Nicotiana benthamiana Provides a Possibility for Rapid Substrate Testing and Production of Novel Compounds;Biotechnology Journal;2018-04-26
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3