Approach to predict the contribution of cytochrome P450 enzymes to drug metabolism in the early drug-discovery stage: The effect of the expression of cytochromeb5with recombinant P450 enzymes-Reference-Cited by-同舟云学术

Approach to predict the contribution of cytochrome P450 enzymes to drug metabolism in the early drug-discovery stage: The effect of the expression of cytochromeb5with recombinant P450 enzymes

Published:2007-09 Issue:9 Volume:37 Page:986-999
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Emoto C.,Iwasaki K.

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.1080/00498250701620692

Reference17 articles.

1. Enzymatic characteristics of CYP3A5 and CYP3A4: A comparison ofin vitrokinetic and drug–drug interaction patterns

2. Approach to the prediction of the contribution of major cytochrome P450 enzymes to drug metabolism in the early drug-discovery stage

3. Evaluation of Approach to Predict the Contribution of Multiple Cytochrome P450s in Drug Metabolism Using Relative Activity Factor: Effects of the Differences in Expression Levels of NADPH–Cytochrome P450 Reductase and Cytochrome b5 in the Expression System and the Differences in the Marker Activities

4. P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature

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