Leukotriene B412-hydroxydehydrogenase/15-ketoprostaglandinΔ13-reductase (LTB412-HD/PGR) responsible for the reduction of a double-bond of theα,β-unsaturated ketone of an aryl propionic acid non-steroidal anti-inflammatory agent CS-670
Author:
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1080/00498250701767667
Reference26 articles.
1. Pharmacological differences between the optical isomers of ibuprofen: evidence for metabolic inversion of the (—)-isomer
2. Disposition of CS-670, a novel nonsteroidal anti-inflammatory drug, and its metabolites in healthy human volunteers
3. Stereospecific Taurine Conjugation of the trans-OH Metabolite (Active Metabolite) of CS-670, a New 2-Arylpropionic Acid Nonsteroidal Anti-inflammatory Drug, in Dogs.
4. Quantitative determination of diol metabolites of CS-670, a new antiinflammatory agent, by capillary column gas chromatography-mass spectrometry
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