Butyrate acts through HDAC inhibition to enhance aryl hydrocarbon receptor activation by gut microbiota-derived ligands

Author:

Modoux Morgane12,Rolhion Nathalie12,Lefevre Jeremie H.23,Oeuvray Cyriane12,Nádvorník Petr4,Illes Peter4,Emond Patrick5,Parc Yann3,Mani Sridhar6,Dvorak Zdenek4,Sokol Harry127ORCID

Affiliation:

1. Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, CRSA, AP-HP, Saint Antoine Hospital, Gastroenterology Department, Paris, France

2. Paris Centre for Microbiome Medicine (PaCeMM) FHU, Paris, France

3. Sorbonne Université, Department of Digestive Surgery, AP-HP, Hôpital Saint Antoine, Paris, France

4. Departments of Cell Biology and Genetics, Palacký University, Olomouc, Czech Republic

5. UMR 1253, iBrain, Université de Tours, Inserm, Tours, Centre-Val de Loire, France

6. Departments of Molecular Pharmacology, Genetics and Medicine, Albert Einstein College of Medicine, Bronx, NY, USA

7. INRAe, UMR1319 Micalis & AgroParisTech, Jouy en Josas, France

Funder

Fondation pour la Recherche Médicale

the European Crohn´s and Colitis Organisation

Czech Science Foundation

the European Research Council

the European Union’s Horizon 2020 Research and Innovation Programme

European Crohn’s and Colitis Organisation

Publisher

Informa UK Limited

Subject

Infectious Diseases,Microbiology (medical),Gastroenterology,Microbiology

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