Gut microbiota from patients with COVID-19 cause alterations in mice that resemble post-COVID symptoms

Author:

Mendes de Almeida Viviani1,Engel Daiane F.2,Ricci Mayra F.1,Cruz Clênio Silva1,Lopes Ícaro Santos3,Alves Daniele Almeida4,d’ Auriol Mirna5,Magalhães João1,Machado Elayne C.1,Rocha Victor M.1,Carvalho Toniana G.6,Lacerda Larisse S. B.7,Pimenta Jordane C.7,Aganetti Mariana1,Zuccoli Giuliana S.8,Smith Bradley J.8,Carregari Victor C.8,da Silva Rosa Erika1,Galvão Izabela1,Dantas Cassali Geovanni9,Garcia Cristiana C.10,Teixeira Mauro Martins7,André Leiliane C.5,Ribeiro Fabiola Mara6,Martins Flaviano S.11,Saia Rafael Simone12,Costa Vivian Vasconcelos7,Martins-de-Souza Daniel8131415,Hansbro Philip M.16,Marques João Trindade417,Aguiar Eric R. G. R.3,Vieira Angélica T.1ORCID

Affiliation:

1. Laboratory of Microbiota and Immunomodulation - Department of Biochemistry and Immunology, Institute of Biological Sciences, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, Brazil

2. Department of Clinical Analysis, School of Pharmacy, Universidade Federal de Ouro Preto - UFOP, Ouro Preto, Brazil

3. Laboratory of Virus Bioinformatics - Department of Biological Science, Center of Biotechnology and Genetics, Universidade Estadual de Santa Cruz - UESC, Ilhéus, Brazil

4. Laboratory of RNA Interference and Antiviral Immunity - Department of Biochemistry and Immunology, Institute of Biological Sciences, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, Brazil

5. Laboratory of Toxicology - Department of Clinical and Toxicological Analysis, Faculty of Pharmacy, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, Brazil

6. Laboratory of Neurobiochemistry - Department of Biochemistry and Immunology, Institute of Biological Sciences, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, Brazil

7. Center for Research and Development of Drugs - Department of Morphology, Institute of Biological Sciences, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, Brazil

8. Laboratory of Neuroproteomics - Department of Biochemistry and Tissue Biology, Institute of Biology, Universidade do Estado de Campinas - UNICAMP, Campinas, Brazil

9. Laboratory of Comparative Pathology - Department of Pathology, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, Brazil

10. Laboratory of Respiratory Viruses and Measles, Instituto Oswaldo Cruz - Fiocruz, Rio de Janeiro, Brazil

11. Laboratory of Biotherapeutic Agents - Department of Microbiology, Institute of Biological Sciences, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, Brazil

12. Laboratory of Intestinal Physiology - Department of Physiology, Ribeirão Preto Medical School, Universidade de São Paulo, Ribeirão Preto, Brazil

13. D’Or Institute for Research and Education, São Paulo, Brazil

14. Experimental Medicine Research Cluster, Universidade do Estado de Campinas - UNICAMP, Campinas, Brazil

15. National Institute of Biomarkers in Neuropsychiatry, National Council for Scientific and Technological Development, São Paulo, Brazil

16. Centre for Inflammation, Centenary Institute and University of Technology Sydney, Sydney, Australia

17. CNRS UPR9022, University of Strasbourg, Strasbourg, France

Funder

National Council for Scientific and Technological Development – CNPq

Instituto Serrapilheira

Pró-Reitoria de Pesquisa da Universidade Federal de Minas Gerais – PRPq

National Health and Medical Research Council of Australia

Publisher

Informa UK Limited

Subject

Infectious Diseases,Microbiology (medical),Gastroenterology,Microbiology

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