Synthesis and anti-Cancer Activity of a New Hybrid Based Spirooxindole-Pyrrolidine -Thiochromene Scaffolds <i>via</i> [3 + 2] Cycloaddition Reaction: Computational Investigation-Reference-Cited by-同舟云学术

Synthesis and anti-Cancer Activity of a New Hybrid Based Spirooxindole-Pyrrolidine -Thiochromene Scaffolds via [3 + 2] Cycloaddition Reaction: Computational Investigation

Published:2022-02-27 Issue:3 Volume:43 Page:2302-2320
ISSN:1040-6638
Container-title:Polycyclic Aromatic Compounds
language:en
Short-container-title:Polycyclic Aromatic Compounds

Author:

Barakat Assem¹^ORCID,Haukka Matti²^ORCID,Soliman Saied M.³^ORCID,Al-Majid Abdullah Mohammed¹,Ali M.¹^ORCID,Islam Mohammad Shahidul¹^ORCID,Karami Abdulnasser Mahmoud¹,Ul-Haq Zaheer⁴^ORCID,Domingo Luis R.⁵^ORCID

Affiliation:

1. Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia

2. Department of Chemistry, University of Jyväskylä, Jyväskylä, Finland

3. Department of Chemistry, Faculty of Science, Alexandria University, Alexandria, Egypt

4. Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

5. Department of Organic Chemistry, University of Valencia, Burjassot, Spain Dr. Moliner 50, Valencia

Publisher

Informa UK Limited

Subject

Materials Chemistry,Organic Chemistry,Polymers and Plastics

Link

https://www.tandfonline.com/doi/pdf/10.1080/10406638.2022.2042334

Reference56 articles.

1. Molecular diversity of spirooxindoles. Synthesis and biological activity

2. Synthesis of novel dispiropyrrolothiazoles by three-component 1,3-dipolar cycloaddition and evaluation of their antimycobacterial activity

3. A strategic approach to the synthesis of functionalized spirooxindole pyrrolidine derivatives: in vitro antibacterial, antifungal, antimalarial and antitubercular studies

4. Antiproliferative effects of mitraphylline, a pentacyclic oxindole alkaloid of Uncaria tomentosa on human glioma and neuroblastoma cell lines

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Pharmacokinetics, MDS, and ADME of Spirooxindole-Pyrrolidines Embedded with Pyrazole Heterocycleas α-Amylase Inhibitor and Potential Cytotoxic Compounds;J BIOL REG HOMEOS AG;2024

2. Spirooxindole derivatives as an anticancer agent;Spirooxindole;2024

3. A novel alpha‐amylase inhibitor‐based spirooxindole‐pyrrolidine‐clubbed thiochromene‐pyrzaole pharmacophores: Unveiling the [3+2] cycloaddition reaction by molecular electron density theory;Chemical Biology & Drug Design;2023-08-10

4. Propagative isatin in organic synthesis of spirooxindoles through catalysis;Tetrahedron;2023-03

5. Exploration of the mechanism, chemospecificity, regiospecificity and stereoselectivity of the cycloaddition reaction between 9α-hydroxyparthenolide and nitrilimine: MEDT study;Theoretical Chemistry Accounts;2022-09-03