A strategic approach to the synthesis of functionalized spirooxindole pyrrolidine derivatives: in vitro antibacterial, antifungal, antimalarial and antitubercular studies-Reference-Cited by-同舟云学术

A strategic approach to the synthesis of functionalized spirooxindole pyrrolidine derivatives: in vitro antibacterial, antifungal, antimalarial and antitubercular studies

Published:2015 Issue:1 Volume:39 Page:520-528
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Haddad Saoussen¹²³⁴²,Boudriga Sarra¹²³⁴,Akhaja Tarunkumar Nanjibhai²⁵⁶⁷⁸,Raval Jignesh Priyakant²⁵⁶⁷⁸,Porzio François²⁹¹⁰¹¹¹²,Soldera Armand²⁹¹⁰¹¹¹²,Askri Moheddine¹²³⁴,Knorr Michael¹³¹⁴¹⁵¹⁶,Rousselin Yoann¹⁷¹⁸¹⁹¹⁶,Kubicki Marek M.¹⁷¹⁸¹⁹¹⁶,Rajani Dhanji²⁰²¹⁸

Affiliation:

1. Laboratory of Heterocyclic Chemistry Natural Products and Reactivity/LCHPNR

2. Department of Chemistry

3. Faculty of Science of Monastir

4. Tunisia

5. UkaTarsadia University

6. Maliba Campus

7. Dist: Surat 394350

8. India

9. Quebec Center for Functional Materials

10. University of Sherbrooke

11. Sherbrooke

12. Canada

13. Institute UTINAM - UMR CNRS 6213

14. University of Franche-Comté

15. F-25030 Besançon

16. France

17. Institute of Molecular Chemistry - UMR CNRS 6302

18. University of Bourgogne

19. F-21078 Dijon

20. Microcare Laboratories

21. Surat – 395001

Abstract

A series of spirooxindole pyrrolidine derivatives has been synthesized and evaluated for theirin vitrobiological activities. The observed regio- and stereoselectivity of the cycloaddition reaction has been rationalized using DFT calculations.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2015/NJ/C4NJ01008F

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